Date Filer Title Filing Type Shares Traded Price Total Held
March 15, 2024 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 25,000 -- 110,688
March 17, 2023 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 40,000 -- 85,688
May 15, 2018 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 100,000 -- 124,643
May 30, 2017 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 21,786 -- 21,786
February 2, 2016 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 40,000 -- 152,500
March 17, 2015 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 37,500 -- 112,500
June 20, 2014 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 5,000 $3.50 5,000
June 20, 2014 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 40,000 -- 40,000
June 20, 2014 Chief Scientific Officer Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 35,000 -- 75,000
February 19, 2019 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 20,000 -- 325,047
May 15, 2018 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 250,000 -- 305,047
May 30, 2017 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 48,571 -- 48,571
September 6, 2016 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 40,663 -- 316,213
February 2, 2016 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 12,000 $1.33 19,926
February 2, 2016 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 275,550
March 17, 2015 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 225,550
June 20, 2014 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 50,000 -- 175,550
February 11, 2014 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 40,000 -- 125,500
May 6, 2013 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 80,000 -- 385,000
June 15, 2012 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 36,250 $2.15 305,000
February 22, 2012 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 13,750 -- 268,750
December 12, 2011 CMO Form 4 Open market or private purchase of non-derivative or derivative security 5,000 $2.00 35,687
March 23, 2011 CMO Form 4 Conversion of derivative security 2,500 $2.40 30,687
March 23, 2011 CMO Form 4 Conversion of derivative security 6 -- --
February 25, 2011 CMO Form 4 Grant, award or other acquisition pursuant to Rule 16b-3(d) 70,000 $2.49 255,000

For recent transactions, including derivative transactions, see our Section 16 SEC filings page.

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.